2021 Mercedes-Benz S-Class

Trims, performance, features, fuel economy, safety and known problems — with the pros and cons against similar 2021 models.

Mercedes-Benz S-Class
Pictured: Mercedes-Benz W223 IMG 6663. Photo: Alexander Migl, CC BY-SA 4.0, via Wikimedia Commons
Class
Large Cars
Body styles
S500 4matic 4dr Sedan Swb, S560 4matic 2dr Coupe, S560 Cabriolet, S580 4matic 4dr Sedan Lwb
Engines
3.0L 6-cyl, 4.0L 8-cyl turbo
Drivetrain
4-Wheel Drive, Rear-Wheel Drive
Fuel
Hybrid, Premium Gasoline
MPG (best)
24 combined · 20 city / 29 hwy
Length
198–209.4 in
Curb weight
4,564–4,817 lb
NHTSA rating
Not rated
Recalls
0 campaigns

Pros & cons

What's good

  • Hybrid version availableOffered as a hybrid as well as gas.
  • AWD / 4WD available
  • No recalls so far

Watch out for

  • Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.

Calculated from EPA, NHTSA and vPIC data against 16 similar 2021 models — not a review. How we calculate this →

Overview

The 2021 Mercedes-Benz S-Class is a large car offered with 2 engines (3.0L 6-cyl and 4.0L 8-cyl turbo), including a hybrid version and 4-wheel drive and rear-wheel drive.

It measures about 205 inches long and 77 inches wide on a 122-inch wheelbase, with a curb weight of roughly 4,610 lb (S500 4matic 4dr Sedan Swb).

EPA rates its most efficient version at 24 MPG combined (20 city / 29 highway), 0% better than the 2021 large car average of 24.1 MPG, for an estimated $3,400 a year in fuel.

NHTSA has not published a 5-Star overall rating for this model year.

There are no recalls or owner complaints on file with NHTSA for this model year.

What changed for 2021

  • New body dimensions: 3.5 in longer, wheelbase +2.3 in — most likely a redesign or new generation
  • New hybrid version
  • No plug-in hybrid version any more
  • Engine added: 3.0L 6-cyl
  • Engines dropped: 3.0L 6-cyl turbo and 6.0L 12-cyl turbo

Compared with 2020; trim, feature and price changes aren't covered. See the 2020 S-Class →

Dimensions & weight

BodyLengthWidthHeightWheelbaseTrack F / RCurb weightWeight F/R
S500 4matic 4dr Sedan Swb205.1 in76.8 in59.1 in122 in65 / 65 in4,610 lb
S560 4matic 2dr Coupe198 in74.8 in55.5 in116.1 in64.2 / 65 in4,795 lb53/47
S560 Cabriolet198 in74.8 in55.9 in116.1 in64.2 / 65 in4,795 lb53/47
S580 4matic 4dr Sedan Lwb209.4 in76.8 in59.1 in126.4 in65 / 65 in4,775 lb
S63 Amg 4matic 2dr Coupe198.4 in74.8 in55.9 in116.1 in64.2 / 65 in4,564 lb53/47
S63 Amg 4matic Cabriolet198.4 in74.8 in56.3 in116.1 in64.2 / 65 in4,817 lb53/47

Transport Canada CVS (Open Government Licence – Canada), Canadian-market figures.

Will it fit your garage? Check with your measurements →

Engines, MPG & running costs

VersionEngineTransmissionDriveCity / Hwy / Combvs. classFuel / yrCO₂ g/mi
S500 4matic Hybrid3.0L 6-cylAutomatic 9-spd4-Wheel Drive20 / 29 / 240%$3,400372
S560 Convertible4.0L 8-cyl turboAutomatic 9-spdRear-Wheel Drive16 / 26 / 20-15%$4,100454
S560 4matic Coupe4.0L 8-cyl turboAutomatic 9-spd4-Wheel Drive16 / 26 / 20-27%$4,100454
S580 4matic Hybrid4.0L 8-cyl turboAutomatic 9-spd4-Wheel Drive17 / 25 / 20-17%$4,100452
AMG S63 4matic Plus Coupe4.0L 8-cyl turboAutomatic 9-spd4-Wheel Drive16 / 26 / 19-31%$4,350471
S580 4matic Maybach Hybrid4.0L 8-cyl turboAutomatic 9-spd4-Wheel Drive16 / 24 / 19-21%$4,350469
AMG S63 4matic Plus Convertible4.0L 8-cyl turboAutomatic 9-spd4-Wheel Drive14 / 24 / 17-27%$4,850510
5/10EPA fuel economy score (best version)
5/10EPA greenhouse gas score
Spend $5,000Fuel over 5 years vs. average new car
24.1 MPG2021 Large Cars average

EPA estimates; "vs. class" is combined MPG against the 2021 EPA class average. How we calculate this →

Safety ratings & technology

NHTSA has not published 5-Star ratings for the 2021 Mercedes-Benz S-Class.

Similar 2021 large cars

ModelBest MPG / rangeNHTSA overallRecalls
2021 Mercedes-Benz S-Class (this car)24 MPGNot rated0
2021 BMW 5 Series28 MPGNot rated0
2021 BMW 7 Series25 MPGNot rated0
2021 Lexus LS28 MPGNot rated2
2021 Tesla Model S405 miNot rated23
2021 Porsche Panamera22 MPGNot rated4
2021 Lexus ES44 MPGNot rated1

Recalls (0)

No vehicle recalls on file with NHTSA for the 2021 Mercedes-Benz S-Class.

Check your VIN for open recalls at NHTSA ↗

Not every 2021 Mercedes-Benz S-Class is affected — only a VIN check confirms your car.

Owner-reported problems

No owner complaints for the 2021 Mercedes-Benz S-Class in NHTSA's database since 2015.

Used 2021 Mercedes-Benz S-Class buyer's checklist

  1. Run the VIN at nhtsa.gov/recalls. No recalls on file, but check anyway.
  2. Hybrid system. Check for hybrid-system warning lights and ask whether the high-voltage battery has been replaced or is still under warranty.
  3. Before you pay: service records, a history report and an independent inspection.

Generated by DecodedCars from NHTSA recalls and owner complaints for the 2021 Mercedes-Benz S-Class. Not a substitute for a professional inspection.

Other S-Class years

Compare all years →
YearMPG (best)LengthOverallRecallsComplaints
2027 S-Class23–Not rated00
2026 S-Class23208.3 inNot rated00
2025 S-Class24208.3 inNot rated00
2024 S-Class24208.3 inNot rated00
2023 S-Class23209.4 inNot rated00
2022 S-Class24205.1 inNot rated00
2020 S-Class23201.6 inNot rated00
2019 S-Class23201.6 inNot rated00
2018 S-Class22201.6 inNot rated00
2017 S-Class26201.6 inNot rated00
2016 S-Class26201.6 inNot rated00
2015 S-Class26201.6 inNot rated00

Sources: EPA, NHTSA, Transport Canada, Wikimedia Commons. Not affiliated with NHTSA, the EPA or Mercedes-Benz. How we calculate this →