Cadillac CT5 vs Lexus IS
2026 Cadillac CT5 vs 2026 Lexus IS — two rivals compared on efficiency, size, safety and reliability.
The short version
The Cadillac CT5 is more fuel-efficient: 26 vs 22 MPG combined in its best version.
That works out to about $600 a year less in fuel for the Cadillac CT5 (EPA estimate, 15,000 miles).
The Cadillac CT5 is the bigger car, about 8 inches longer.
Across all model years since 2005, the Cadillac CT5 has had fewer recall campaigns (6 vs 15).
The two cars
The 2026 Cadillac CT5 is a midsize car offered with 3 engines (2.0L 4-cyl turbo, 3.0L 6-cyl turbo and 6.2L 8-cyl) and rear-wheel drive and all-wheel drive. It measures about 194 inches long and 74 inches wide on a 116-inch wheelbase, with a curb weight of roughly 3,799 lb (4dr Sedan AWD).
The 2026 Lexus IS is a compact car offered with a 3.5L 6-cyl engine and rear-wheel drive and all-wheel drive. It measures about 186 inches long and 72 inches wide on a 110-inch wheelbase, with a curb weight of roughly 3,913 lb.
Buying used? The 2024 CT5 and the 2024 IS have the fewest problems in our data; avoid the 2020 CT5 and the 2015 IS.
Basics
Efficiency
Performance & space
Safety & reliability
Interest
Green = clearly better. Prices are not included. How we calculate this →
Which one should you choose?
Choose the Cadillac CT5 if…
- You want lower fuel bills (26 vs 22 MPG)
- You want more room (8 in longer)
- You want more standard driver-assist tech
- You put reliability history first (6 vs 15 recalls since 2005)
Choose the Lexus IS if…
- You want something easier to park (8 in shorter)
Pros & cons of each
2026 Cadillac CT5
- AWD / 4WD available
- Lots of standard safety tech4 of 5 key driver aids standard on the versions we checked.
- Below-average fuel economyBest version gets 26 MPG combined, 17% below the 2026 midsize car average of 31.2 MPG.
- Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.
2026 Lexus IS
- AWD / 4WD available
- Lots of standard safety tech5 of 5 key driver aids standard on the versions we checked.
- Below-average fuel economyBest version gets 22 MPG combined, 25% below the 2026 compact car average of 29.2 MPG.
- Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.
Full 2026 Cadillac CT5 specs →Full 2026 Lexus IS specs →Compare fuel costs for your driving →Compare size & garage fit →

