Cadillac CT5 vs Lexus IS

2026 Cadillac CT5 vs 2026 Lexus IS — two rivals compared on efficiency, size, safety and reliability.

Cadillac CT5

2026 Cadillac CT5

Midsize CarsAWD/4WD
VS4 – 2Cadillac CT5 wins 4 of 6 categories
Lexus IS

2026 Lexus IS

Compact CarsAWD/4WD

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The short version

The Cadillac CT5 is more fuel-efficient: 26 vs 22 MPG combined in its best version.

That works out to about $600 a year less in fuel for the Cadillac CT5 (EPA estimate, 15,000 miles).

The Cadillac CT5 is the bigger car, about 8 inches longer.

Across all model years since 2005, the Cadillac CT5 has had fewer recall campaigns (6 vs 15).

The two cars

The 2026 Cadillac CT5 is a midsize car offered with 3 engines (2.0L 4-cyl turbo, 3.0L 6-cyl turbo and 6.2L 8-cyl) and rear-wheel drive and all-wheel drive. It measures about 194 inches long and 74 inches wide on a 116-inch wheelbase, with a curb weight of roughly 3,799 lb (4dr Sedan AWD).

The 2026 Lexus IS is a compact car offered with a 3.5L 6-cyl engine and rear-wheel drive and all-wheel drive. It measures about 186 inches long and 72 inches wide on a 110-inch wheelbase, with a curb weight of roughly 3,913 lb.

Buying used? The 2024 CT5 and the 2024 IS have the fewest problems in our data; avoid the 2020 CT5 and the 2015 IS.

Basics

Midsize Cars
Class
Compact Cars
Premium Gasoline
Fuel
Premium Gasoline
2.0L 4-cyl turbo, 3.0L 6-cyl turbo, 6.2L 8-cyl
Engines
3.5L 6-cyl
Rear-Wheel Drive, All-Wheel Drive
Drivetrain
Rear-Wheel Drive, All-Wheel Drive

Efficiency

26 MPG
Best combined MPG
22 MPG
22 city
City / highway MPG (best)
19 city
$3,150
Fuel cost per year (EPA)
$3,750

Performance & space

–
Horsepower (most powerful)
311 hp
–
Seats (most)
5
193.7 in
Length
185.8 in
74 in
Width
72.4 in
57.1 in
Height
56.3 in
3,660 lb
Curb weight (lightest)
3,913 lb

Safety & reliability

15
Driver-assist features standard
11
1
Recalls (2026)
0
6
Recalls, all years since 2005
15
6
Owner complaints (latest year)
1

Interest

9,415
Wikipedia views, 30 days
28,367

Buying used

Best used year
Year to avoid

Green = clearly better. Prices are not included. How we calculate this →

Which one should you choose?

Choose the Cadillac CT5 if…

  • You want lower fuel bills (26 vs 22 MPG)
  • You want more room (8 in longer)
  • You want more standard driver-assist tech
  • You put reliability history first (6 vs 15 recalls since 2005)

Choose the Lexus IS if…

  • You want something easier to park (8 in shorter)

Pros & cons of each

2026 Cadillac CT5

  • AWD / 4WD available
  • Lots of standard safety tech4 of 5 key driver aids standard on the versions we checked.
  • Below-average fuel economyBest version gets 26 MPG combined, 17% below the 2026 midsize car average of 31.2 MPG.
  • Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.

2026 Lexus IS

  • AWD / 4WD available
  • Lots of standard safety tech5 of 5 key driver aids standard on the versions we checked.
  • Below-average fuel economyBest version gets 22 MPG combined, 25% below the 2026 compact car average of 29.2 MPG.
  • Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.

Full 2026 Cadillac CT5 specs →Full 2026 Lexus IS specs →Compare fuel costs for your driving →Compare size & garage fit →