DecodedCarsAlfa Romeo Giulia vs Mercedes-Benz E-Class
2026 Alfa Romeo Giulia vs 2026 Mercedes-Benz E-Class — two midsize cars compared on efficiency, size, safety and reliability.
The short version
The Mercedes-Benz E-Class is more fuel-efficient: 28 vs 27 MPG combined in its best version.
That works out to about $100 a year less in fuel for the Mercedes-Benz E-Class (EPA estimate, 15,000 miles).
Across all model years since 2005, the Mercedes-Benz E-Class has had fewer recall campaigns (0 vs 17).
The two cars
The 2026 Alfa Romeo Giulia is a midsize car offered with a 2.0L 4-cyl turbo engine and rear-wheel drive and all-wheel drive. EPA rates its most efficient version at 27 MPG combined (24 city / 33 highway), 13% worse than the 2026 midsize car average of 31.2 MPG, for an estimated $3,050 a year in fuel.
The 2026 Mercedes-Benz E-Class is a midsize car offered with 2 engines (2.0L 4-cyl turbo and 3.0L 6-cyl turbo), including a hybrid version and rear-wheel drive and all-wheel drive. It measures about 195 inches long and 75 inches wide on a 117-inch wheelbase, with a curb weight of roughly 5,269 lb (Amg 4dr Sedan).
Buying used? The 2023 Giulia and the 2024 E-Class have the fewest problems in our data; avoid the 2018 Giulia.
Basics
Efficiency
Performance & space
Safety & reliability
Interest
Green = clearly better. Prices are not included. How we calculate this →
Which one should you choose?
Choose the Alfa Romeo Giulia if…
It doesn't clearly beat the Mercedes-Benz E-Class on any measure we track.
Choose the Mercedes-Benz E-Class if…
- You want a hybrid or electric option
- You put reliability history first (0 vs 17 recalls since 2005)
Pros & cons of each
2026 Alfa Romeo Giulia
- AWD / 4WD available
- Below-average fuel economyBest version gets 27 MPG combined, 13% below the 2026 midsize car average of 31.2 MPG.
- Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.
2026 Mercedes-Benz E-Class
- Hybrid version availableOffered as a hybrid and plug-in hybrid as well as gas.
- AWD / 4WD available
- Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.
Full 2026 Alfa Romeo Giulia specs →Full 2026 Mercedes-Benz E-Class specs →Compare fuel costs for your driving →Compare size & garage fit →